Last modified on 16 August 2002.

Literature Reference:

Mears J.A., Cannone J.J., Stagg S.M., Gutell R.R., Agrawal, R.K., and Harvey S.C. (2002)
Modeling a Minimal Ribosome Based on Comparative Sequence Analysis.
Journal of Molecular Biology, 321:215-234.

Manuscript Figures and Tables:

Abbreviations Used: Conservation: 3P, Three Phylogenetic Domains; 3P2O, Three Phylogenetic Domains/Two Organelles. rRNAs: LSU, large subunit rRNA; SSU, small subunit rRNA.
Figure/Table Legend Panel
Table 1. Comparative analysis. ( HTML )
Table 2. Protein conservation. ( HTML )
Table 3. Deletions in the C. elegans alignment. ( HTML )
Table 4. Bridges conserved through evolution. ( HTML )
Table 5. Conserved tRNA/rRNA contacts within the ribosome. ( HTML )
Table 6. 16S and 23S rRNA Sequences Used for Comparative Analysis. ( HTML )
Figure 1. Conserved regions of the ribosome. A, 3P / SSU; B, 3P / LSU; C, 3P2O / SSU; D, 3P2O / LSU. ( JPG )
Figure 2. The polypeptide-conducting tunnel. A, 3P; B, 3P2O. ( JPG )
Figure 3. C. elegans alignment mapped onto secondary structures. A. SSU ( JPG | PS )
B. LSU ( JPG | PS )
Figure 4. C. elegans alignment mapped onto crystal structures. A, SSU; B, LSU. ( JPG )
Figure 5. Positioning of bridge contacts. ( JPG )
Figure 6. Probability of movement. A, LSU Helix 94; B, LSU Helices 47-61. ( JPG )

Additional Figures and Tables:

CONS.5 and CONS.1 are five-column and one-column presentations of the conservation data, respectively.
tRNA/mRNA Binding Site vs. rRNA Conservation ( List of Positions ) ( Data Table )
rRNA Nucleotide Numbering/Conservation Tables: 16S rRNA: ( CONS.5 | CONS.1 ) 23S rRNA: ( CONS.5 | CONS.1 )

rRNA Conservation Diagrams:

Phylogenetic Group 16S rRNA 23S rRNA
Three Phylogenetic Domains ( PS | PDF ) 5' half: ( PS | PDF ) -- 3' half: ( PS | PDF )
Three Phylogenetic Domains/Two Organelles ( PS | PDF ) 5' half: ( PS | PDF ) -- 3' half: ( PS | PDF )