Table 4: Further Grouping of Class I and II LPTLs Based on the LPTL-RNA Interaction Pattern

^* Triloop sequences were based on the more than 50% conservation for the single nucleotide frequencies in the three phylogenetic domains³⁷, R = purines (A or G) and Y = pyrimidines (C or U).
LPTL Groups (Triloop Sequence^*)	LPTL-RNA Interaction	Class I		Class II		Total
LPTL Groups (Triloop Sequence^*)	LPTL-RNA Interaction	Type A	Type B	Type A	Type B	Total
Total		7	10	2	2	21
R1 (UGNRA, GGNRG)	X or X+Y	5	1	2	0	8
R2 (UUYRA)	Y	2	0	0	0	2
R3 (NUAAN, NRNAN)	Z	0	5	0	2	7
R4 (NRYAN)	Y+Z	0	2	0	0	2
R5 (NCNUN)	-	0	2	0	0	2

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