Correlation of RNA Secondary Structure Statistics with Thermodynamic Stability and Applications to Folding: Table 1

Last modified on 18 April 2012.

Table 1. Statistical energy derived from sequences of each specified molecule

	No. nucleotides	No. sequences	Corr coef	SD
Bacterial 16S rRNA	1,468,052	319	0.870	0.507
Bacterial 5S rRNA	34,443	96	0.477	1.194
Eukaryotic 5S rRNA	95,778	263	0.857	0.677
tRNA	148,248	650	0.833	0.988
All sequence	1,746,521	1,328	0.862	0.525
PDB-derived²⁹	7,424^a	N/A	0.7764	0.8138

For statistical energies derived from the sequences of each specified molecule, the number of nucleotides in base-pair stacks, correlation coefficient and standard deviation compared with experimental base-pair stack energies are presented. 50 The last row lists equivalent information for PDB-derived statistical potentials.

²⁹ Dima RI, Hyeon C, and Thirumalai D (2005). Extracting stacking interaction parameters for RNA from the data set of native structures. Journal of Molecular Biology, 347:53-69.

^a Number of bases in stacks.

Comparative RNA Web Site and Project The Gutell Lab

Correlation of RNA Secondary Structure Statistics with Thermodynamic Stability and Applications to Folding: Table 1

Table 1. Statistical energy derived from sequences of each specified molecule